Honolulu police have reopened Kamehameha Hwy. near Kualoa Ranch after a head-on crash.
The call came in at 1:14 p.m. near Tropical Farms macadamia nut farm.
According to Emergency Medical Services, the two female drivers, who are in their 50s, were taken to the hospital in serious condition.
Crews had to shut down the road for several hours to remove wreckage.