Lanikuhana Avenue in Mililani has reopened in both directions from Kamehameha Hwy. to Anania St. after a crash.
Officials say a car hit a pole at around 8:45 a.m.
According to Emergency Medical Services, a 28-year-old woman and a 30-year-old man were hospitalized in serious condition.
The road was reopened just before 10:45 a.m.