Pali Highway was completely shut down in the Kailua-bound direction due to a crash Tuesday night.
According to police dispatch, the two-vehicle crash occurred at around 8:12 p.m. in the left lane before the tunnels.
Police say a 22-year-old Kailua woman apparently lost control of her vehicle, drifted into the opposite flow of traffic, and was broadsided by a car.
She was hospitalized in critical condition.
Two men in the Kailua-bound car were not hurt.
Police say speed and alcohol do not appear to be factors in the crash.